Indwara zimpyiko zidakira (CKD) zifite hyperphosharetemia, kandi hyperphosharemia ndende irashobora kuganisha ku bigo bya kabiri nka hyperparathyroididism, renal osteodyrophy, n'indwara z'umutima. Igenzura rya phosporus yamaraso ni igice cyingenzi mubuyobozi bwabarwayi CKD, na fosifate ni ibiyobyabwenge mfunzwe kugirango bivure hyperphosphamia. Mu myaka yashize,Lanthanum Carbonate, nkubwoko bushya bwabatari calcium na batavuga ba fosifate binder, buhoro buhoro binjiye buhoro buhoro murwego rwabantu kandi batangira "amarushanwa" na pasiporo gakondo.
"Ibitekerezo" na "Demesi" by'Abadepite gakondo
Umuyoboro wa Fositori gakondo urimo ahanini ahagaragara calcium (nka calcium carbonate na calcium acetate) na aluminimu-birimo imiyoboro ya fosifari (nka aluminiyumu hydroxide). Bahuza na fosifate mubiribwa kugirango bakore ibintu bidahujwe, bityo bikagabanya kwinjira kwa Fositori.
Calcium-ikubiyemo ibikoresho bya fosifate: Igiciro gito kandi gisobanutse neza, ariko gukoresha igihe kirekire birashobora kuganisha kuri hypercallemia no kongera ibyago byo kubara imirahamwe.
Aluminum-irimo FOSPhorus Bunders: ingaruka zikomeye za fosifurusi, ariko guhuza na aluminium ni uburozi bwinshi kandi birashobora gutera indwara y'amagufwa ya aluminium na encephalopathis, kandi kuri ubu birakoreshwa.
Lanthanum Carbonate: Ringcomer, hamwe nibyiza bikomeye
Lanthanum Carbonate ni karone ya sicyuma cyicyuma cyisi Lanthanum, hamwe nuburyo budasanzwe bwa fosifori buhuza. Irekura ions ya lanthanum mubidukikije bya acide yinzira isuzugure kandi ifite ubuhanga bwa lintham hamwe na fosifari hamwe na fosifari hamwe na fosifate, bityo bikabuza fosifate.
Kumenyekanisha muri make Lanthanum karobonate
| Izina ry'ibicuruzwa | Lanthanum Carbonate |
| Formula | La2 (Co3) 3.xh2o |
| Kas Oya | 648-39-4 |
| Uburemere bwa molekile | 457.85 (anhy) |
| Ubucucike | 2.6 G / CM3 |
| Gushonga | N / a |
| Isura | Ifu yera |
| Kudashoboka | Gushonga mumazi, humura cyane muri acide ikomeye |
| Gushikama | Byoroshye hygroscopic |
Ugereranije na FOSPHORUS gakondo, Lanthanum Carbonate ifite ibyiza bikurikira:
NTA CABCUM na Aluminium, umutekano wo hejuru: wirinde uburozi bwa hypercalcemia na aluminimu, cyane cyane abarwayi bafite ubuvuzi bwigihe kirekire ndetse ningaruka zo kubara imizi.
FOSPHORUS ikomeye ihuza ubushobozi, ingaruka zikomeye zo kugabanya fosphorus zirashobora guhuza phuskhorus murugero runini ph, kandi ubushobozi bwabwo bukomeye bukomeye kuruta fosifori gakondo.
Ibisubizo bike mubisubizo, kubara neza: Lanthanum Carbonate iraryoshye, biroroshye gufata, bifite uburakari buke, kandi abarwayi birashoboka cyane ko bakurikiza kwivuza igihe kirekire.
Ibimenyetso byubushakashatsi byubuvuzi: Lanthanum Carbonate ikora neza
Ubushakashatsi bwinshi bwa clinical bwemeje imikorere n'umutekano wa LANTRAM CARBONATE kubarwayi ba CKD. Ubushakashatsi bwerekanye ko Lanthanum Carbonate ntabwo iri munsi cyangwa iruta imirongo gakondo ya fosifori mu kugabanya urugero rwa positori, kandi irashobora kugenzura neza urwego rwa IPTH kandi zinoza ibipimo byamagufwa. Byongeye kandi, umutekano wo kuvurwa igihe kirekire hamwe na lanthanum karubone nibyiza, kandi ntagushinyagurika kugaragara na lanthatham hamwe nibisubizo byuburozi byabonetse.
Kuvura kugiti cyihariye: Hitamo gahunda nziza kumurwayi
Nubwo Lanthanum Carbonate ifite ibyiza byinshi, ntibisobanura ko bishobora gusimbuza burundu imishinga gakondo ya fosifate. Buri muti ufite icyerekezo cyacyo nitumanaho, kandi gahunda yo kuvura igomba kugiti cye hakurikijwe ibintu byihariye byumurwayi.
Lanthanum Carbonate irakwiriye kubarwayi bakurikira:
Abarwayi bafite hypercallemia cyangwa ibyago bya hypercallemia
Abarwayi bafite imizabibu cyangwa ibyago byo kubara imizabibu
Abarwayi bafite uburwayi buke cyangwa imikorere mibi ya fosichate gakondo
Umuyoboro gakondo wa Fositori urashobora gukoreshwa kubarwayi bakurikira:
Abarwayi bafite ubukungu buke
Abarwayi ballergique cyangwa kutihanganira lanthanum carbonate
Kureba ejo hazaza: Lanthanum Carbonate ifite ejo hazaza heza
Hamwe no kwimbitse ubushakashatsi bwa kavukire no kwegeranya uburambe bwa kuvura, imiterere ya Lanthanum Carbonate mu kuvura hyperphosharemia mu barwayi ba CKD izakomeza gutera imbere. Mugihe kizaza, biteganijwe ko hazateganijwe kuba umurongo wa mbere wa fosifate binder, uzana inkuru nziza kubarwayi benshi ba CKD.
Igihe cya nyuma: Werurwe-25-2025